Scientists have managed to cut down cancer spread in the body by about three-quarters in an experiment conducted on animals, reports BBC Health.
This promising study published in the Nature, was done on a mouse. It was able to alter the immune system and lower the rate of spread of cancer in the body.
The UK Cancer Research stated that this study opened new doors in understanding the spread of tumor- information that can be used to develop new treatments.
The body is ever fighting with the rapidly mutating cancer and needs external boost to cut down this cancer spread also called metastasis.
The team from Sanger Institute in Cambridge was focused on understanding the ways tumor spreads in the body.
How the study was done
Researchers created 810 sets of genetically modified lab mice to discover which sections of the DNA were involved in the body resisting a cancer’s spread.
The researches then injected the animals with skin cancer and kept a count of the tumors that developed in the lung.
Their study discovered that 23 sections of DNA either encouraged or discouraged the spread of cancer.
Most of these are instrumental in the immune system.
They then shifted focus on the Spns2 gene leading to a cut in spread of cancer by 75%.
Via BBC Health
One of the team members told BBC that this assisted in regulating the immune cells within the lungs.
“It changes the balance of cells that play a role in killing tumour cells and those that switch off the immune system,” said Dr David Adams.
Some patients have witnessed tremendous help with immunotherapy – harnessing the power of the immune system to fight cancer.
As much as these drugs have assisted some patients, they have failed to be effective in some.
“We’ve learnt some interesting new biology that we might be able to use – it’s told us this gene is involved in tumour growth,” said Dr Adams.